Phosphodiesterase inhibitor

Definición:

Phosphodiesterase inhibitor
A phosphodiesterase inhibitor is a drug that blocks one or more of the five subtypes of the enzyme phosphodiesterase (PDE), therefore preventing the inactivation of the intracellular second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s).

Phosphodiesterase inhibitor forma parte de las siguientes categorías:

inhibitor
a substance that retards or stops an activity
sustantivo
Enzyme inhibitor; Feedback inhibition; Auto-induction; Auto-inhibition; Irreversible inhibition; ...
Inhibidor enzimático
Enzyme inhibitors are molecules that bind to enzymes and decrease their activity
sustantivo

subcategorías de Phosphodiesterase inhibitor:

PDE5 inhibitor
A phosphodiesterase type 5 inhibitor, often shortened to PDE5 inhibitor, is a drug used to block the degradative action of phosphodiesterase type 5 on cyclic GMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of the penis
sustantivoimage
caffein; Caffeine
Cafeína
a bitter alkaloid found in coffee and tea that is responsible for their stimulating effects
sustantivoimage
Theobromine; Riddospas; Riddovydrin; Santheose; Seominal; ...
Teobromina
Theobromine, also known as xantheose, is a bitter alkaloid of the cacao plant, found in chocolate, as well as in a number of other foods, including the leaves of the tea plant, and the kola or cola nut
sustantivoimage
Theophylline; Accurbron; Aquaphyllin; Asmalix; Theofylline; ...
Teofilina
Theophylline, also known as dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as COPD or asthma under a variety of brand names
sustantivoimage
Dipyridamole; Persantin; Persantine; Dipyramidol
Dipyridamole (also known commercially by Persantine) is a drug that inhibits thrombus formation when given chronically and causes vasodilation when given at high doses over short time.
sustantivoimage
Papaverine
Papaverina
Papaverine is an opium alkaloid used primarily in the treatment of visceral spasm, vasospasm (especially those involving the heart and the brain), and occasionally in the treatment of erectile dysfunction
sustantivoimage
HT-0712
HT-0712 is an experimental cognitive enhancing drug which is currently undergoing clinical trials
sustantivoimage
Pentoxifylline; Trental
Pentoxifilina
Pentoxifylline is the International Nonproprietary Name (INN) of a drug sold by Aventis under the brand name Trental
sustantivoimage
Cilostazol; Pletal
Cilostazol is a medication used in the alleviation of the symptom of intermittent claudication in individuals with peripheral vascular disease
sustantivoimage
Aminophylline
Aminophylline is a bronchodilator
sustantivoimage
Anagrelide; Agrylin
Anagrelide is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia)
sustantivoimage
Paraxanthine
Paraxanthine, or 1,7-dimethylxanthine, is a dimethyl derivative of xanthine, structurally related to caffeine
sustantivoimage
Tofisopam; Emandaxin; Grandaxin
Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a drug which is a benzodiazepine derivative
sustantivoimage
Vinpocetine; Intellectol; Ethyl apovincaminate; Cavinton; Intelectol
Vinpocetina
Vinpocetine is a semisynthetic derivative alkaloid of vincamine, an extract from the periwinkle (plant) Vinca minor
sustantivoimage
Milrinone; Primacor
Milrinona
Milrinone (Primacor) is a phosphodiesterase III inhibitor
sustantivoimage
Amrinone; Inamrinone lactate
Amrinone or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a type 3 pyridine phosphodiesterase inhibitor.
sustantivoimage
Enoximone
Enoximone (INN, trade name Perfan) is an imidazole phosphodiesterase inhibitor
sustantivo
Bucladesine
Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor
sustantivoimage
Rolipram
Rolipram is a PDE4-inhibitor
sustantivoimage
EHNA
EHNA (erythro-9-adenine) is a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type-2 (PDE2).
sustantivoimage